垂杨柳医院
作者:刘家伦、姜树东
腰椎管狭窄是指各种形式引起的中央椎管、侧隐窝以及椎间孔的狭窄,进而引起神经根或马尾神经受压并出现相应神经功能障碍的一类疾病。单侧双通道脊柱内镜技术(Unilateral biportal endoscopic, UBE)技术在治疗腰椎管狭窄时有着得天独厚的优势[1],可在充分减压的同时最大程度保留后方解剖结构,降低术后脊柱不稳的发生率[2-5]。UBE技术处理腰椎管狭窄时既拥有微创的优势,又具备操作的高效,在临床上取得了优异的效果,被誉为“为狭窄而生”的技术[6-7]。
一、UBE治疗腰椎管狭窄的难点1.UBE治疗多节段腰椎管狭窄:对于多节段的腰椎管狭窄,目前大多采取开放手术进行治疗。而UBE技术的出现为多节段腰椎管狭窄的手术治疗提供了新思路。
但采用UBE技术治疗多节段腰椎管狭窄有以下难点:(1)手术节段多,手术时间长,操作难度大;(2)多节段操作时(左侧为例),中间的切口既要作为下位节段的观察通道,也要作为上位节段的操作通道,切口定位难度大;(3)多节段腰椎管狭窄,责任节段的定位。
建议
1.国内有医生采用双人双侧同时进行手术来缩短手术时长,为UBE的多节段操作提供了新思路。
2.要重视椎管减压窗这一概念,中间切口建议定位于相邻减压窗的中心位置,这样可以让操作和观察得以兼顾。
3.应结合患者主诉、查体及影像学资料进行综合性判断,若多节段狭窄而责任节段为单节段,则可先解决单节段病灶。
2.UBE治疗重度腰椎管狭窄:对于重度腰椎管狭窄,术前更需仔细进行影像学判读,合理规划减压范围。既要保证减压效果,又要避免对关节突关节过多的侵扰,达到缓解症状又不影响脊柱稳定性的效果。
UBE技术治疗重度腰椎管狭窄有以下难点:(1)腰椎退变严重,椎板间隙难以辨认;(2)关节突内聚严重,若需彻底减压,关节突关节切除较多;(3)硬膜外粘连,黄韧带和硬膜囊之间无空间,易造成医源性损伤,或者硬膜菲薄引起迟发性脑脊液漏。
建议
1.既然没有椎板间隙,便自行造一个间隙,可通过术中透视,通过椎体及周围结构确定开窗位置,用磨钻为退化的椎板开一个间隙(图1),再以此为基准完成后续操作。
2.可将切口适当内移,通过倾斜角度处理内聚的上、下关节突,避免对关节突关节切除过多或减压范围不足(图2)。
3.应操作更加轻柔,仔细剥离黄韧带与硬膜间隙,如果无法剥离保留部分黄韧带可以接受。
图1 UBE术中解剖结构
图2 UBE术中切除内聚的上关节突
二、UBE治疗腰椎管狭窄的技术要点1.定位:应用UBE技术治疗腰椎管狭窄时,目前较常用的通道为[8-9]:①以上下椎体椎弓根內缘连线和椎间隙水平线交点为基点,分别向远、近端1-1.5cm为工作通道和内镜通道。②后正中线与椎间隙水平线交点以外1cm为工作通道,再向近端至少3cm建立内镜通道(左侧为例),不宜过近,以免对操作造成干扰。
建议
对于UBE的定位,要重视“减压窗”的概念,一切操作都是为减压服务的。建议术前评估好减压范围,并找到“减压窗”上下限和椎弓根內缘的交点。我们术中通过X线透视找到这2个交点的体表投影,以这2个点位为切口可更好控制减压范围(图3)。
图3 基于减压窗定位(a:规划减压范围;b:减压边界体表投影标记;c:减压上边界近端器械垂直于皮肤;d:减压下边界远端器械垂直于皮肤)
2.减压:对于减压环节,建议按照一定顺序进行已达到简单、有序、高效的效果。以单侧为例,顺序为:上位椎板下缘、下位椎板上缘、下关节突、上关节突。在此过程中,要特别注意侧隐窝区和Corner区的减压,减压时要找到“椎弓根內缘”这一标志以确定骨性开窗足够。同时,可应用神经钩对神经根进行张力检查以确保减压充分。
3.止血:在术中操作时,出血往往会影响手术视野以影响手术进度。针对出血问题。
建议
1.对于可预料的出血可采用预止血;
2.止血时并非要将视野放在中心,可适当调整视野到出血点“上游”,这样可以更好地看到出血点(图4);
3.全身应用氨甲环酸、局部应用止血纱布填塞出血区有助于减少出血。
图4 镜头放置在出血点“上游”可清楚看到出血点
三、并发症的处理UBE技术的并发症包括硬膜囊撕裂、硬膜外血肿、神经组织损伤、医源性脊柱不稳、减压不彻底、早期复发、感染、术后腰痛、术后头痛、腹膜后积液、贫血等[10-13]。其中,硬膜外血肿的发生率最高,其次是硬膜囊撕裂以及减压不彻底[14-15]。Kim等[16]报道,术后MRI可检测到的硬膜外血肿发生率达23.6%,但是出现症状的血肿发生率为1.9%。Park等[17]对42篇文献共3673例病例的并发症进行了荟萃分析,发现硬膜外血肿、硬膜囊撕裂以及减压不彻底的发生率分别为3.79%、2.23%、1.29%。
建议
针对硬膜外血肿的预防,有以下策略[18-22]:
1.将水压维持在2.41-22.84mmHg,过高会导致患者颅内压升高,可能引发麻醉恢复后的疼痛,而压力过低会影响术野进而导致手术时间延长。
2.术前详细规划手术方案,进行模拟手术,尽量缩短手术时长。
3.术中尽量彻底止血,酌情使用止血材料,放置引流管引流。
硬膜囊撕裂好发于硬膜囊背侧区域,由于生理盐水的灌注,使得硬膜囊在中间形成折叠并隐藏于硬膜外脂肪下,若未考虑到这一解剖关系,则易在黄韧带切除时造成硬膜囊撕裂[23-24]。部分患者的硬膜囊极其菲薄,术中应特别关注,硬膜囊越趋于透明则证明硬膜囊越菲薄。
建议
对于硬膜囊撕裂,有以下处理措施[25-29]:
1.撕裂口较小时无需缝合,引流管放置观察通道多留置数日,通常可自行愈合;
2.撕裂口较大时,若切口较规则,可采用镜下缝合;
3.撕裂口较大、神经根疝出较多,可考虑开放手术进行修补。
减压不彻底主要表现为术后患者症状无改善甚至加重,该情况尤其好发于学习曲线早期阶段。主要影响因素包括:术者操作熟练度、椎间盘钙化及腰椎严重退变等[11,15]。针对减压不彻底,术者可通过熟悉腰椎各节段结构特点、椎板咬除范围、黄韧带起止点、椎间盘定位以及硬膜囊和神经根的保护来减少该情况的发生[30]。
参考文献[1] 汪文龙, 刘正, 吴四军, 等. 单侧双通道内镜下减压治疗腰椎管狭窄症的早期疗效观察[J]. 中国脊柱脊髓杂志, 2021, 31(10): 911-918.
Wenlong Wang, Zheng Liu, Sijun W. U. Preliminary Clinical Outcomes of Unilateral Biportal Endoscopy for Decompressing Lumbar Spinal Steno-Sis[J]. Chinese Journal of Spine and Spinal Cord, 2021, 31(10): 911-918.
[2] 李冬月, 苏庆军, 张希诺, 等. 单侧双通道脊柱内镜技术治疗退变性腰椎疾病对术后腰椎稳定性影响的临床研究[J]. 中华外科杂志, 2024, 62(3): 187-193.
Li Dong Yue, Su Qing Jun, Zhang Xi Nuo, et al. Clinical Study of Lumbar Stability After Unilateral Biportal Endoscopy in the Treatment of Degenerative Lumbar Diseases[J]. Chinese Journal of Surgery, 2024, 62(3): 187-193.
[3] Akbary K, Kim J S, Park C W, et al. Biportal Endoscopic Decompression of Exiting and Traversing Nerve Roots through a Single Interlaminar Window Using a Contralateral Approach: Technical Feasibilities and Morphometric Changes of the Lumbar Canal and Foramen[J]. World Neurosurg, 2018, 117: 153-161.
[4] Ito F, Ito Z, Shibayama M, et al. Step-by-Step Sublaminar Approach with a Newly-Designed Spinal Endoscope for Unilateral-Approach Bilateral Decompression in Spinal Stenosis[J]. Neurospine, 2019, 16(1): 41-51.
[5] Kim H S, Paudel B, Jang J S, et al. Percutaneous Full Endoscopic Bilateral Lumbar Decompression of Spinal Stenosis through Uniportal-Contralateral Approach: Techniques and Preliminary Results[J]. World Neurosurg, 2017, 103: 201-209.
[6] Tan B, Yang Q Y, Fan B, et al. Decompression Via Unilateral Biportal Endoscopy for Severe Degenerative Lumbar Spinal Stenosis: A Comparative Study with Decompression Via Open Discectomy[J]. Front Neurol, 2023, 14: 1132698.
[7] Hu Y, Fu H, Yang D, et al. Clinical Efficacy and Imaging Outcomes of Unilateral Biportal Endoscopy with Unilateral Laminotomy for Bilateral Decompression in the Treatment of Severe Lumbar Spinal Stenosis[J]. Front Surg, 2022, 9: 1061566.
[8] Wang Y, Maimaiti A, Tuoheti A, et al. The Method of Portal Making in Lumbar Unilateral Biportal Endoscopic Surgery with Different Operative Approaches According to the Constant Anatomical Landmarks of the Lumbar Spine: A Review of the Literature[J]. Global Spine J, 2024, 14(6): 1838-1861.
[9] Hwa E J, Hwa H D, Son S K, et al. Percutaneous Biportal Endoscopic Decompression for Lumbar Spinal Stenosis: A Technical Note and Preliminary Clinical Results[J]. J Neurosurg Spine, 2016, 24(4): 602-607.
[10] Lin G X, Huang P, Kotheeranurak V, et al. A Systematic Review of Unilateral Biportal Endoscopic Spinal Surgery: Preliminary Clinical Results and Complications[J]. World Neurosurg, 2019, 125: 425-432.
[11] Kim W, Kim S K, Kang S S, et al. Pooled Analysis of Unsuccessful Percutaneous Biportal Endoscopic Surgery Outcomes From a Multi-Institutional Retrospective Cohort of 797 Cases[J]. Acta Neurochir (Wien), 2020, 162(2): 279-287.
[12] Akbary K, Kim J S, Park C W, et al. The Feasibility and Perioperative Results of Bi-Portal Endoscopic Resection of a Facet Cyst Along with Minimizing Facet Joint Resection in the Degenerative Lumbar Spine[J]. Oper Neurosurg (Hagerstown), 2020, 18(6): 621-628.
[13] Kim J E, Choi D J, Park E J. Evaluation of Postoperative Spinal Epidural Hematoma After Biportal Endoscopic Spine Surgery for Single-Level Lumbar Spinal Stenosis: Clinical and Magnetic Resonance Imaging Study[J]. World Neurosurg, 2019, 126: e786-e792.
[14] Park H J, Kim S K, Lee S C, et al. Dural Tears in Percutaneous Biportal Endoscopic Spine Surgery: Anatomical Location and Management[J]. World Neurosurg, 2020, 136: e578-e585.
[15] Choi D J, Choi C M, Jung J T, et al. Learning Curve Associated with Complications in Biportal Endoscopic Spinal Surgery: Challenges and Strategies[J]. Asian Spine J, 2016, 10(4): 624-629.
[16] Kim J E, Choi D J, Kim M C, et al. Risk Factors of Postoperative Spinal Epidural Hematoma After Biportal Endoscopic Spinal Surgery[J]. World Neurosurg, 2019, 129: e324-e329.
[17] Park D Y, Upfill-Brown A, Curtin N, et al. Clinical Outcomes and Complications After Biportal Endoscopic Spine Surgery: A Comprehensive Systematic Review and Meta-Analysis of 3673 Cases[J]. Eur Spine J, 2023, 32(8): 2637-2646.
[18] Hong Y H, Kim S K, Hwang J, et al. Water Dynamics in Unilateral Biportal Endoscopic Spine Surgery and its Related Factors: An in Vivo Proportional Regression and Proficiency-Matched Study[J]. World Neurosurg, 2021, 149: e836-e843.
[19] Ahn J S, Lee H J, Choi D J, et al. Extraforaminal Approach of Biportal Endoscopic Spinal Surgery: A New Endoscopic Technique for Transforaminal Decompression and Discectomy[J]. J Neurosurg Spine, 2018, 28(5): 492-498.
[20] Kim J E, Yoo H S, Choi D J, et al. Effectiveness of Gelatin-Thrombin Matrix Sealants (Floseal(R)) On Postoperative Spinal Epidural Hematoma During Single-Level Lumbar Decompression Using Biportal Endoscopic Spine Surgery: Clinical and Magnetic Resonance Image Study[J]. Biomed Res Int, 2020, 2020: 4801641.
[21] Taha M M, Elsharkawy A M, Al M H, et al. Spontaneous Cervical Epidural Hematoma: A Case Report and Review of Literature[J]. Surg Neurol Int, 2019, 10: 247.
[22] Kang T, Park S Y, Lee S H, et al. Spinal Epidural Abscess Successfully Treated with Biportal Endoscopic Spinal Surgery[J]. Medicine (Baltimore), 2019, 98(50): e18231.
[23] Lee H G, Kang M S, Kim S Y, et al. Dural Injury in Unilateral Biportal Endoscopic Spinal Surgery[J]. Global Spine J, 2021, 11(6): 845-851.
[24] Hong Y H, Kim S K, Suh D W, et al. Novel Instruments for Percutaneous Biportal Endoscopic Spine Surgery for Full Decompression and Dural Management: A Comparative Analysis[J]. Brain Sci, 2020, 10(8).
[25] 苟鹏国, 高刚, 井万里, 等. 经皮单侧双通道内镜手术治疗腰椎退变性疾病的研究进展[J]. 中华创伤骨科杂志, 2023, 25(7): 640-644.
Gou Peng Guo, Gao Gang, Jing Wan Li, et al. Clinical Progress in Percutaneous Unilateral Biportal Endoscopic Surgery for Degenerative Lumbar Diseases[J]. Chinese Journal of Orthopaedic Trauma, 2023, 25(7): 640-644.
[26] Heo D H, Ha J S, Lee D C, et al. Repair of Incidental Durotomy Using Sutureless Nonpenetrating Clips Via Biportal Endoscopic Surgery[J]. Global Spine J, 2022, 12(3): 452-457.
[27] Grannum S, Patel M S, Attar F, et al. Dural Tears in Primary Decompressive Lumbar Surgery. Is Primary Repair Necessary for a Good Outcome?[J]. Eur Spine J, 2014, 23(4): 904-908.
[28] Soliman H M. Irrigation Endoscopic Discectomy: A Novel Percutaneous Approach for Lumbar Disc Prolapse[J]. Eur Spine J, 2013, 22(5): 1037-1044.
[29] Kim J E, Choi D J, Park E J. Risk Factors and Options of Management for an Incidental Dural Tear in Biportal Endoscopic Spine Surgery[J]. Asian Spine J, 2020, 14(6): 790-800.
[30] 刘续文, 朱斌, 王其飞, 等. 腰椎间盘突出患者腰椎Ct三维重建影像的解剖学测量及其在单边双通道内镜手术中的临床意义[J]. 中华解剖与临床杂志, 2022, 27(9): 608-613.
Liu Xu Wen, Zhu Bin, Wang Qi Fei, et al. Ct Three-Dimensional Reconstruction and Measurement of Lumbar Spine in Patients with Lumbar Disc Herniation and its Clinical Significance in Unilateral Biportal Endoscopic Technique[J]. Chinese Journal of Anatomy and Clinics, 2022, 27(9): 608-613.
作者简介姜树东
清华大学附属垂杨柳医院脊柱外科主任,主任医师,学科带头人,加拿大英属哥伦比亚大学博士后
中国老年学和老年医学学会老年骨科分会常务委员
中国老年学和老年医学学会老年骨科分会脊柱微创学组组长
中国康复医学会眩晕康复专业委员会常务委员
中国康复医学会颈椎病专业委员会常务委员
中国康复医学会颈椎病专业委员会人工间盘置换学组学组常务委员
北京市眩晕研究会理事
刘家伦
清华大学附属垂杨柳医院脊柱外科医师
医学硕士毕业,从事脊柱相关疾病的临床和科研工作,发表多篇中英文核心文章和编著
声明:此文内容及图片由供稿单位提供,仅供学习交流,不代表骨科在线观点。